Pendant la révolution mexicaine du début du XXe siècle, Tita de la Garza et Pedro Múzquiz, deux âmes profondément amoureuses, ne peuvent être ensemble à cause de coutumes familiales trop ancrées. Tita, en lutte contre le destin que lui impose sa famille trouve refuge dans la cuisine. C'est sa façon à elle de résister et de canaliser ses désirs les plus profonds dans ses recettes, transformant ceux qui les goûtent.
Forced to help prepare for a wedding between her beloved and her sister, a heartbroken Tita throws her emotions into the cake, sparking Nacha’s memories of her own tragic love story with Miguel. Meanwhile, as trouble brews between his father and his friend Juan, Pedro chooses a side.
After Rosaura sends heartbreaking news to the family, Tita not only loses all desire to cook but finally finds the courage to stand up to her mother. Meanwhile, a vindictive Pedro leads Gertrudis and the rest of the revolutionaries into a battle with his uncle, and Elena seizes back her power – with devastating consequences.